This paper summarises William G. Grigsby’ s contribution to our understanding of neighbourhood change. We discuss seven contributions among Grigsby’ s most-lasting. First, he staked out the boundaries of the still-nascent field very early in his career. Secondly, he situated the subject within the broader framework of metropolitan housing market dynamics. Thirdly, he developed a theoretical framework for investig ating the subject that featured the analysis of housing sub-markets, the market process of neighbourhood succession, and residential segregation. Fourthly, he identified the economic, social, institutional and demographic forces that create neighbourhood change. Fifthly, he linked neighbourhood decline and deteriora tion to the spatial concentration of poverty. Sixthly, he underscore d the significance of this understanding for formulating public policies to deal with deteriora ted neighbourhoods. And seventhly, he provided a remarkably complete and robust framework for analysing neighbourhood change. This last-mentioned contribution is the culmination of his lifetime work and will prove perhaps to be his most significant. It provides a road map to future research on neighbourhood dynamics that others may wish to follow.